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Acid reflux and heartburn medicines: prices in the US

Updated 2026-11-04 · USD · United States

2 active ingredients in this group have medicine guides for the US. Medicines in one group are not interchangeable: which one suits you is a question for a doctor or pharmacist.

Active ingredientBrandsLowest listed
OmeprazoleOmeprazole, PrilosecOmeprazole 20mg tablet: $9.99
PantoprazolePantoprazolePantoprazole : $2.00

Listed prices as shown on each pharmacy’s website, checked October 27, 2026. This is a dated snapshot, not a live price, and excludes delivery fees, discounts and insurance cover. Prices change often, so confirm on the pharmacy site before you buy.

Whether Acid reflux and heartburn medicines needs a prescription in the US depends on the strength and pack size. Ask a pharmacist before you buy.

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All United States medicine price guides